Be careful with interpretation here. There are a couple things to keep in mind: 1) Note that some of those runs valid at that time have the center already inland, and thus show a higher central pressure just for that reason. 2) The ECMWF, though it has a relatively high resolution, still doesn't have enough to properly resolve a tropical cyclone inner core, nor do the other global models (although they are approaching that capability with time). There could be other effects such as numerical grid-scale issues that can give unreasonable central pressures, etc.
So, when evaluating a TC's presentation in the global model fields, don't focus too much on the details such as the model predicted minimum central pressure, but rather on larger scale features such as the packing of the isobars, the size of the circulation, whether the circulation is strengthening or weakening in the model, what the upper level shear profile looks like, and so on.
My take on this is that the global models have trended toward showing a strengthening and tightening system once Isaac moves into the central Gulf, which means that they are in general agreement that conditions should be favorable for strengthening there, perhaps significant strengthening. Beyond that, we have no skill in forecasting exactly how much.
*edited by southerngale to remove IMG tags from quoteEDIT: Ooops, my bad southerngale...
< kind of what gfs and euro have been doing with eachother as of lately.. IMO
